diff --git a/src/nix/deployment/mod.rs b/src/nix/deployment/mod.rs
index 7b19dca..da25324 100644
--- a/src/nix/deployment/mod.rs
+++ b/src/nix/deployment/mod.rs
@@ -28,7 +28,7 @@ use super::{
     host::Local as LocalHost,
     key::{Key, UploadAt as UploadKeyAt},
     ColmenaError, ColmenaResult, CopyDirection, CopyOptions, Hive, Host, NodeConfig, NodeName,
-    Profile, ProfileDerivation, RebootOptions,
+    Profile, ProfileDerivation, RebootOptions, StorePath,
 };
 
 /// A deployment.
@@ -637,7 +637,18 @@ impl Deployment {
                 }
             }
 
-            host.activate(&profile_r, arc_self.goal).await?;
+            let activation_program: &StorePath =
+              &arc_self.hive
+              .get_registry_config()
+              .await?
+              .systems
+              .get(target.config.system_type.as_ref().unwrap_or(&"nixos".to_owned()))
+              .expect(&format!("System type {} does not exists",
+                  target.config.system_type.as_ref().unwrap_or(&"nixos".to_owned())
+                  ))
+              .activation_program;
+
+            host.activate(&profile_r, arc_self.goal, activation_program).await?;
 
             job.success_with_message(arc_self.goal.success_str().to_string())?;
 
diff --git a/src/nix/hive/options.nix b/src/nix/hive/options.nix
index a35ef81..2b65de3 100644
--- a/src/nix/hive/options.nix
+++ b/src/nix/hive/options.nix
@@ -258,6 +258,12 @@ with builtins; rec {
         type = types.functionTo types.unspecified;
         default = _: {};
       };
+      activationProgram = lib.mkOption {
+        description = mdDoc ''
+          Program to execute at activation time.
+        '';
+        type = types.path;
+      };
     };
   };
   registryOptions = { lib, ... }: let
diff --git a/src/nix/host/local.rs b/src/nix/host/local.rs
index a5bf0df..681394b 100644
--- a/src/nix/host/local.rs
+++ b/src/nix/host/local.rs
@@ -78,7 +78,12 @@ impl Host for Local {
         Ok(())
     }
 
-    async fn activate(&mut self, profile: &Profile, goal: Goal) -> ColmenaResult<()> {
+    async fn activate(
+        &mut self,
+        profile: &Profile,
+        goal: Goal,
+        activation_program: &StorePath,
+    ) -> ColmenaResult<()> {
         if !goal.requires_activation() {
             return Err(ColmenaError::Unsupported);
         }
@@ -91,7 +96,9 @@ impl Host for Local {
         }
 
         let command = {
-            let activation_command = profile.activation_command(goal).unwrap();
+            let activation_command = profile
+                .activation_command(goal, activation_program)
+                .unwrap();
             self.make_privileged_command(&activation_command)
         };
 
diff --git a/src/nix/host/mod.rs b/src/nix/host/mod.rs
index 8ff44ad..531c26c 100644
--- a/src/nix/host/mod.rs
+++ b/src/nix/host/mod.rs
@@ -128,6 +128,7 @@ pub trait Host: Send + Sync + std::fmt::Debug {
         profile: &Profile,
         goal: Goal,
         copy_options: CopyOptions,
+        activation_program: Option<&StorePath>,
     ) -> ColmenaResult<()> {
         self.copy_closure(
             profile.as_store_path(),
@@ -137,7 +138,12 @@ pub trait Host: Send + Sync + std::fmt::Debug {
         .await?;
 
         if goal.requires_activation() {
-            self.activate(profile, goal).await?;
+            self.activate(
+                profile,
+                goal,
+                activation_program.expect("Unknown activation program"),
+            )
+            .await?;
         }
 
         Ok(())
@@ -171,7 +177,12 @@ pub trait Host: Send + Sync + std::fmt::Debug {
     ///
     /// The profile must already exist on the host. You should probably use deploy instead.
     #[allow(unused_variables)]
-    async fn activate(&mut self, profile: &Profile, goal: Goal) -> ColmenaResult<()> {
+    async fn activate(
+        &mut self,
+        profile: &Profile,
+        goal: Goal,
+        activation_program: &StorePath,
+    ) -> ColmenaResult<()> {
         Err(ColmenaError::Unsupported)
     }
 
diff --git a/src/nix/host/ssh.rs b/src/nix/host/ssh.rs
index 64ebb68..ae3952c 100644
--- a/src/nix/host/ssh.rs
+++ b/src/nix/host/ssh.rs
@@ -90,7 +90,12 @@ impl Host for Ssh {
         Ok(())
     }
 
-    async fn activate(&mut self, profile: &Profile, goal: Goal) -> ColmenaResult<()> {
+    async fn activate(
+        &mut self,
+        profile: &Profile,
+        goal: Goal,
+        activation_program: &StorePath,
+    ) -> ColmenaResult<()> {
         if !goal.requires_activation() {
             return Err(ColmenaError::Unsupported);
         }
@@ -101,7 +106,9 @@ impl Host for Ssh {
             self.run_command(set_profile).await?;
         }
 
-        let activation_command = profile.activation_command(goal).unwrap();
+        let activation_command = profile
+            .activation_command(goal, activation_program)
+            .unwrap();
         let v: Vec<&str> = activation_command.iter().map(|s| &**s).collect();
         let command = self.ssh(&v);
         self.run_command(command).await
diff --git a/src/nix/mod.rs b/src/nix/mod.rs
index a1a0b6b..000135a 100644
--- a/src/nix/mod.rs
+++ b/src/nix/mod.rs
@@ -101,6 +101,9 @@ pub struct MetaConfig {
 pub struct SystemTypeConfig {
     #[serde(rename = "supportsDeployment")]
     pub supports_deployment: bool,
+
+    #[serde(rename = "activationProgram")]
+    pub activation_program: StorePath,
 }
 
 #[derive(Debug, Clone, Validate, Deserialize)]
diff --git a/src/nix/profile.rs b/src/nix/profile.rs
index b71c637..752e3a4 100644
--- a/src/nix/profile.rs
+++ b/src/nix/profile.rs
@@ -26,7 +26,11 @@ impl Profile {
     }
 
     /// Returns the command to activate this profile.
-    pub fn activation_command(&self, goal: Goal) -> Option<Vec<String>> {
+    pub fn activation_command(
+        &self,
+        goal: Goal,
+        activation_program: &StorePath,
+    ) -> Option<Vec<String>> {
         if let Some(goal) = goal.as_str() {
             let path = self.as_path().join("bin/switch-to-configuration");
             let switch_to_configuration = path